换一批
换一批Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment.
作者：
Katharina,Bolsewig [1]
;
Eline A J,Willemse [2]
;
Pascual,Sánchez-Juan [3]
;
Alberto,Rábano [4]
;
Minerva,Martínez [4]
;
James D,Doecke [5]
;
Giovanni,Bellomo [6]
;
Lisa,Vermunt [7]
;
Daniel,Alcolea [8]
;
Steffen,Halbgebauer [9]
;
Sjors,In 't Veld [10]
;
Niklas,Mattsson-Carlgren [11]
;
Katerina,Veverova [12]
;
Christopher J,Fowler [13]
;
Lynn,Boonkamp [10]
;
Marleen,Koel-Simmelink [10]
;
Zulaiga,Hussainali [10]
;
Daimy N,Ruiters [10]
;
Lorenzo,Gaetani [6]
;
Andrea,Toja [6]
;
Juan,Fortea [8]
;
Yolande,Pijnenburg [14]
;
Afina W,Lemstra [14]
;
Wiesje M,van der Flier [15]
;
Jakub,Hort [12]
;
Markus,Otto [16]
;
Oskar,Hansson [17]
;
Lucilla,Parnetti [6]
;
Colin L,Masters [13]
;
Alberto,Lleó [8]
;
Charlotte E,Teunissen [10]
;
Marta,Del Campo Milán [18]
作者单位：
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands. k.bolsewig@amsterdamumc.nl.;Amsterdam Neuroscience, Neurodegeneration program, Amsterdam UMC, Amsterdam, The Netherlands. k.bolsewig@amsterdamumc.nl.
[1]
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands.;Multiple Sclerosis Centre and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), Department of Biomedicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland.;Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.;Department of Neurology, University Hospital and University of Basel, Basel, Switzerland.
[2]
Centro de Investigación Biomédica en Red en enfermedades neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.;Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII, Madrid, Spain.
[3]
Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII, Madrid, Spain.
[4]
Australian E-Health Research Centre, CSIRO, Herston, QLD, Australia.
[5]
Section of Neurology, Laboratory of Clinical Neurochemistry, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
[6]
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands.;Amsterdam Neuroscience, Neurodegeneration program, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
[7]
Centro de Investigación Biomédica en Red en enfermedades neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.;Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain.
[8]
Department of Neurology, University Hospital Ulm, Ulm, Germany.;German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany.
[9]
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands.;Amsterdam Neuroscience, Neurodegeneration program, Amsterdam UMC, Amsterdam, The Netherlands.
[10]
Clinical Memory Research Unit, Lund University, Lund, Sweden.;Neurology Clinic, Skåne University Hospital, Lund, Sweden.;Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
[11]
Memory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
[12]
Florey Institute, The University of Melbourne, Melbourne, VIC, Australia.
[13]
Amsterdam Neuroscience, Neurodegeneration program, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
[14]
Amsterdam Neuroscience, Neurodegeneration program, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Epidemiology & Biostatistics, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
[15]
Department of Neurology, University Hospital Ulm, Ulm, Germany.
[16]
Clinical Memory Research Unit, Lund University, Lund, Sweden.
[17]
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, Amsterdam, The Netherlands.;Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.;Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.;Hospital del Mar Research Institute (IMIM), Barcelona, Spain.
[18]
主题词
人类(Humans);Lewy体病(Lewy Body Disease);多巴脱羧酶(Dopa Decarboxylase);男(雄)性(Male);女(雌)性(Female);老年人(Aged);帕金森病(Parkinson Disease);老年人, 80以上(Aged, 80 and over);中年人(Middle Aged);多巴胺药(Dopamine Agents);队列研究(Cohort Studies);纵向研究(Longitudinal Studies)
DOI
10.1038/s41467-025-56293-z
PMID
39881147
发布时间
2025-02-04
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Nature communications
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