Health-related quality of life and symptoms in patients with previously untreated, locally advanced or metastatic non-squamous non-small cell lung cancer treated with sintilimab or placebo plus pemetrexed and platinum (ORIENT-11): A randomized, double-blind, phase 3 trial.

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第一作者： Tingting,Liu

第一单位： Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China.

作者： Tingting,Liu ^[1] ; Junyi,He ^[1] ; Yalan,Wang ^[1] ; Yuwen,Yang ^[1] ; Lin,Zhang ^[1] ; Mengting,Shi ^[1] ; Jiaqing,Liu ^[2] ; Dongcheng,Sun ^[1] ; Zhehai,Wang ^[3] ; Jian,Fang ^[4] ; Qitao,Yu ^[5] ; Baohui,Han ^[6] ; Shundong,Cang ^[7] ; Gongyan,Chen ^[8] ; Xiaodong,Mei ^[9] ; Zhixiong,Yang ^[10] ; Yan,Huang ^[1] ; Wenfeng,Fang ^[1] ; Yunpeng,Yang ^[11] ; Yuanyuan,Zhao ^[12] ; Li,Zhang ^[13]

作者单位： Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. ^[1] Department of Intensive Care Unit, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. ^[2] Medical Oncology Department, Shandong Cancer Hospital, Jinan, Shandong, PR China. ^[3] Department of Thoracic Oncology II, Peking University Cancer Hospital, Beijing, PR China. ^[4] Department of Respiratory Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning City, Guangxi, PR China. ^[5] Department of Respiration, Shanghai Chest Hospital, Shanghai, PR China. ^[6] Department of Oncology, The Henan Province Hospital of Zhengzhou University, Zhengzhou, Henan, PR China. ^[7] Department of Respiration, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, PR China. ^[8] Department of Respiration, Anhui Provincial Hospital, Hefei, Anhui, PR China. ^[9] Department of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China. ^[10] Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address: yangyp@sysucc.org.cn. ^[11] Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address: zhaoyy@sysucc.org.cn. ^[12] Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China. Electronic address: zhangli@sysucc.org.cn. ^[13]

关键词 EORTC-QLQ-C30 Health-related quality of life LCSS Non-small cell lung cancer Sintilimab