换一批
换一批Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence.
第一作者：
Julius,Keyl
第一单位：
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany.;Institute of Pathology, University Hospital Essen (AöR), Essen, Germany.
作者：
Julius,Keyl [1]
;
Philipp,Keyl [2]
;
Grégoire,Montavon [3]
;
René,Hosch [4]
;
Alexander,Brehmer [4]
;
Liliana,Mochmann [5]
;
Philipp,Jurmeister [5]
;
Gabriel,Dernbach [6]
;
Moon,Kim [4]
;
Sven,Koitka [7]
;
Sebastian,Bauer [8]
;
Nikolaos,Bechrakis [9]
;
Michael,Forsting [10]
;
Dagmar,Führer-Sakel [11]
;
Martin,Glas [12]
;
Viktor,Grünwald [13]
;
Boris,Hadaschik [14]
;
Johannes,Haubold [15]
;
Ken,Herrmann [16]
;
Stefan,Kasper [8]
;
Rainer,Kimmig [17]
;
Stephan,Lang [18]
;
Tienush,Rassaf [19]
;
Alexander,Roesch [20]
;
Dirk,Schadendorf [21]
;
Jens T,Siveke [22]
;
Martin,Stuschke [23]
;
Ulrich,Sure [24]
;
Matthias,Totzeck [19]
;
Anja,Welt [25]
;
Marcel,Wiesweg [8]
;
Hideo A,Baba [26]
;
Felix,Nensa [27]
;
Jan,Egger [4]
;
Klaus-Robert,Müller [28]
;
Martin,Schuler [29]
;
Frederick,Klauschen [30]
;
Jens,Kleesiek [31]
作者单位：
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany.;Institute of Pathology, University Hospital Essen (AöR), Essen, Germany.
[1]
Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.;BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany.
[2]
BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany.;Machine Learning Group, Technical University of Berlin, Berlin, Germany.;Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany.
[3]
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany.
[4]
Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany.
[5]
Machine Learning Group, Technical University of Berlin, Berlin, Germany.
[6]
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany.;Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (AöR), Essen, Germany.
[7]
Department of Medical Oncology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.
[8]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Ophthalmology, University Hospital Essen (AöR), Essen, Germany.
[9]
Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.
[10]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;Department of Endocrinology, Diabetes and Metabolism, University Hospital Essen (AöR), Essen, Germany.
[11]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Division of Clinical Neurooncology, Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Medicine Essen, University Duisburg-Essen, Essen, Germany.
[12]
Department of Medical Oncology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Urology, University Hospital Essen (AöR), Essen, Germany.
[13]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Urology, University Hospital Essen (AöR), Essen, Germany.
[14]
Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.
[15]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Nuclear Medicine, University Hospital Essen (AöR), Essen, Germany.
[16]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;Department of Gynecology and Obstetrics, University Hospital Essen (AöR), Essen, Germany.
[17]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;Department of Otorhinolaryngology, University Hospital Essen (AöR), Essen, Germany.
[18]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen (AöR), Essen, Germany.
[19]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Dermatology, University Hospital Essen (AöR), Essen, Germany.
[20]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Dermatology, University Hospital Essen (AöR), Essen, Germany.;Research Alliance Ruhr, Research Center One Health, University of Duisburg-Essen, Essen, Germany.
[21]
Department of Medical Oncology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen (AöR), University of Duisburg-Essen, Essen, Germany.;Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.
[22]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Radiotherapy, University Hospital Essen (AöR), Essen, Germany.
[23]
Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.;Department of Neurosurgery and Spine Surgery, University Hospital Essen (AöR), Essen, Germany.
[24]
Department of Medical Oncology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany.
[25]
Institute of Pathology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.
[26]
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany.;Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (AöR), Essen, Germany.;Medical Faculty, University of Duisburg-Essen, Essen, Germany.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany.
[27]
BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany. klaus-robert.mueller@tu-berlin.de.;Machine Learning Group, Technical University of Berlin, Berlin, Germany. klaus-robert.mueller@tu-berlin.de.;Department of Artificial Intelligence, Korea University, Seoul, South Korea. klaus-robert.mueller@tu-berlin.de.;MPI for Informatics, Saarbrücken, Germany. klaus-robert.mueller@tu-berlin.de.
[28]
Department of Medical Oncology, University Hospital Essen (AöR), Essen, Germany. Martin.Schuler@uk-essen.de.;Medical Faculty, University of Duisburg-Essen, Essen, Germany. Martin.Schuler@uk-essen.de.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany. Martin.Schuler@uk-essen.de.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany. Martin.Schuler@uk-essen.de.
[29]
Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany. Frederick.Klauschen@med.uni-muenchen.de.;BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany. Frederick.Klauschen@med.uni-muenchen.de.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Berlin partner site, Berlin, Germany. Frederick.Klauschen@med.uni-muenchen.de.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Munich partner site, Munich, Germany. Frederick.Klauschen@med.uni-muenchen.de.;Bavarian Cancer Research Center (BZKF), Erlangen, Germany. Frederick.Klauschen@med.uni-muenchen.de.
[30]
Institute for Artificial Intelligence in Medicine, University Hospital Essen (AöR), Essen, Germany. Jens.Kleesiek@uk-essen.de.;Medical Faculty, University of Duisburg-Essen, Essen, Germany. Jens.Kleesiek@uk-essen.de.;West German Cancer Center, University Hospital Essen (AöR), Essen, Germany. Jens.Kleesiek@uk-essen.de.;German Cancer Consortium (DKTK), Partner site University Hospital Essen (AöR), Essen, Germany. Jens.Kleesiek@uk-essen.de.
[31]
主题词
人类(Humans);人工智能(Artificial Intelligence);肿瘤(Neoplasms);治疗结果(Treatment Outcome);预后(Prognosis);电子健康病历(Electronic Health Records);肺肿瘤(Lung Neoplasms);男(雄)性(Male);女(雌)性(Female)
DOI
10.1038/s43018-024-00891-1
PMID
39885364
发布时间
2025-03-01
- 浏览0
Nature cancer
Nature cancer
2025年6卷2期
307-322页
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