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Decreased T helper 1 cell function underlies recurrent sinopulmonary infections in the 17q12 deletion syndrome.

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第一作者： Junghee J,Shin

第一单位： Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Section of Pulmonary, Allergy, Immunology and Sleep Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: junghee.shin@yale.edu.

作者： Junghee J,Shin ^[1] ; Hyeon Jun,Shin ^[2] ; Alan,Gutierrez ^[3] ; Noelle,Yoo ^[3] ; Jennefer,Par-Young ^[3] ; Lais,Osmani ^[3] ; Min Sun,Shin ^[3] ; Pedro A,Sanchez-Lara ^[4] ; Richard,Bucala ^[3] ; Gary,Soffer ^[5] ; Insoo,Kang ^[6]

作者单位： Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Section of Pulmonary, Allergy, Immunology and Sleep Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: junghee.shin@yale.edu. ^[1] Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. ^[2] Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. ^[3] Section of Medical Genetics, Department of Pediatrics, Guerin Children's at Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. ^[4] Section of Pulmonary, Allergy, Immunology and Sleep Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA. ^[5] Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: insoo.kang@yale.edu. ^[6]

关键词 17q12 deletion syndrome CD4 T cells IFN-γ T helper 1 T-bet TBX21