The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability.

导出 OA

翻译打印收藏纠错

第一作者： Emily,Graham

第一单位： Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

作者： Emily,Graham ^[1] ; Lucia,Rampazzo ^[1] ; Chin Wei Brian,Leung ^[1] ; Jacob,Wall ^[1] ; Emőke Zsanett,Gerőcz ^[1] ; Mikhail,Liskovykh ^[2] ; Nikolay,Goncharov ^[2] ; Xanita,Saayman ^[1] ; Ramazan,Gundogdu ^[3] ; Masato T,Kanemaki ^[4] ; Hiroshi,Masumoto ^[5] ; Vladimir,Larionov ^[2] ; Natalay,Kouprina ^[2] ; Fumiko,Esashi ^[6]

作者单位： Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. ^[1] Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ^[2] Sir William Dunn School of Pathology, University of Oxford, Oxford, UK; Department of Pharmacy Services, Vocational School of Health Services, Bingol University, Bingol, Türkiye. ^[3] Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Shizuoka, Japan; Department of Advanced Studies, SOKENDAI, Shizuoka, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. ^[4] Laboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818d, Japan. ^[5] Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. Electronic address: fumiko.esashi@path.ox.ac.uk. ^[6]

关键词 BRCA2 CENP-A CP: Molecular biology HAC HR MLH1 MMR PALB2 centromeres chromosomes exo-FISH

主题词人类(Humans);BRCA2蛋白质(BRCA2 Protein);DNA错配修复(DNA Mismatch Repair);着丝粒(Centromere);细胞存活(Cell Survival);核蛋白质类(Nuclear Proteins)

DOI 10.1016/j.celrep.2025.115259

PMID 39893637

发布时间 2025-02-28

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交