Ondansetron alleviates testosterone-induced BPH in rats through cross regulation of the 5-HT/AR/P-STAT3 and the non-canonical NF-κB pathways.
第一作者:
Reem A,Mohamed
第一单位:
Department of Pharmacology and Toxicology, Faculty of Pharmacy, October University for Modern Sciences and Arts, 26 July Mehwar Road intersection with Wahat Road, 6th of October City, 12451, Egypt. Electronic address: Ralia@msa.edu.eg.
作者:
主题词
动物(Animals);男(雄)性(Male);STAT3转录因子(STAT3 Transcription Factor);昂丹司琼(Ondansetron);睾酮(Testosterone);NF-κB(NF-kappa B);大鼠(Rats);前列腺增生(Prostatic Hyperplasia);信号传导(Signal Transduction);受体, 雄激素(Receptors, Androgen);血清素(Serotonin);大鼠, Wistar(Rats, Wistar);氧化性应激(Oxidative Stress);前列腺(Prostate)
DOI
10.1016/j.ejphar.2025.177331
PMID
39894432
发布时间
2025-02-17
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