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Proposal of real-world solutions for the implementation of predictive biomarker testing in patients with operable non-small cell lung cancer.

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第一作者： Paul,Hofman

第一单位： Laboratory of Clinical and Experimental Pathology, IHU RespirERA, FHU OncoAge, IRCAN, Biobank 0033-00025, Pasteur Hospital, University Côte d'Azur, Nice, France. Electronic address: hofman.p@chu-nice.fr.

作者： Paul,Hofman ^[1] ; Petros,Christopoulos ^[2] ; Nicky,D'Haene ^[3] ; John,Gosney ^[4] ; Nicola,Normanno ^[5] ; Ed,Schuuring ^[6] ; Ming-Sound,Tsao ^[7] ; Christine,Quinn ^[8] ; Jayne,Russell ^[8] ; Katherine E,Keating ^[8] ; Fernando,López-Ríos ^[9]

作者单位： Laboratory of Clinical and Experimental Pathology, IHU RespirERA, FHU OncoAge, IRCAN, Biobank 0033-00025, Pasteur Hospital, University Côte d'Azur, Nice, France. Electronic address: hofman.p@chu-nice.fr. ^[1] Department of Thoracic Oncology, Thoraxklinik and National Center for Tumour Diseases at Heidelberg University Hospital, Heidelberg, Germany. ^[2] Department of Pathology, Hopital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles, Brussels, Belgium. ^[3] Cellular Pathology, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK. ^[4] Scientific Directorate, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy. ^[5] Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. ^[6] Princess Margaret Cancer Center, University Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. ^[7] Diaceutics PLC, Dataworks at Kings Hall Health and Wellbeing Park, Belfast, UK. ^[8] Department of Pathology, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Research Institute Hospital Universitario 12 de Octubre (i+12). CIBERONC, Madrid, Spain. ^[9]

关键词 Early-stage lung cancer Genomic testing Immune checkpoint inhibitors Operable non-small cell lung cancer Precision medicine Predictive biomarkers Targeted therapy

医学主题词人类(Humans);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);肺肿瘤(Lung Neoplasms)

DOI 10.1016/j.lungcan.2025.108107

PMID 39904223

发布时间 2025-05-05

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