Mineralised bone properties in a child with recessive osteogenesis imperfecta type XIV and in a conditional Tmem38b knockout murine model (Runx2-Cre; Tmem38b<sup>fl/fl</sup>).

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第一作者： Chloe E,Jones

第一单位： Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital, Vienna, Austria.

作者： Chloe E,Jones ^[1] ; Stéphane,Blouin ^[2] ; Adalbert,Raimann ^[3] ; Gabriel,Mindler ^[4] ; Barbara M,Contento ^[5] ; Roberta,Besio ^[5] ; Andreas,Kranzl ^[6] ; Benjamin,Kraler ^[4] ; Markus A,Hartmann ^[2] ; Antonella,Forlino ^[5] ; Nadja,Fratzl-Zelman ^[7]

作者单位： Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital, Vienna, Austria. ^[1] Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital, Vienna, Austria; Vienna Bone and Growth Centre, Vienna, Austria. ^[2] Vienna Bone and Growth Centre, Vienna, Austria; Department of Paediatrics and Adolescent Medicine, Division of Paediatric Pulmonology, Allergology and Endocrinology, Medical University of Vienna, Vienna, Austria. ^[3] Vienna Bone and Growth Centre, Vienna, Austria; Department of Paediatric Orthopaedics, Orthopaedic Hospital Speising, Vienna, Austria. ^[4] Department of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy. ^[5] Vienna Bone and Growth Centre, Vienna, Austria; Laboratory for Gait and Movement Analysis, Orthopaedic Hospital Speising, Vienna, Austria. ^[6] Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital, Vienna, Austria; Vienna Bone and Growth Centre, Vienna, Austria. Electronic address: nadja.fratzl-zelman@lbg.ac.at. ^[7]

关键词 Bone matrix mineralisation Osteocyte lacunae Osteocyte lacuno-canalicular network TMEM38B TRIC-B