换一批Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y global registry.
第一作者：
Alessio,Cortellini
第一单位：
Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy a.cortellini@policlinicocampus.it.;Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, UK.;Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
作者：
Alessio,Cortellini [1]
;
Leonardo,Brunetti [2]
;
Giuseppina Rita,Di Fazio [3]
;
Edoardo,Garbo [4]
;
David J,Pinato [5]
;
Jarushka,Naidoo [6]
;
Artur,Katz [7]
;
Monica,Loza [8]
;
Joel W,Neal [8]
;
Carlo,Genova [9]
;
Scott,Gettinger [10]
;
So Yeon,Kim [10]
;
Ritujith,Jayakrishnan [10]
;
Talal,El Zarif [10]
;
Marco,Russano [11]
;
Federica,Pecci [4]
;
Alessandro,Di Federico [4]
;
Mark,Awad [4]
;
Joao V,Alessi [4]
;
Michele,Montrone [12]
;
Dwight Hall,Owen [13]
;
Diego,Signorelli [14]
;
Mary Jo,Fidler [15]
;
Mingjia,Li [16]
;
Andrea,Camerini [17]
;
Andrea,De Giglio [18]
;
Lauren,Young [19]
;
Bruno,Vincenzi [3]
;
Giulio,Metro [20]
;
Francesco,Passiglia [21]
;
Sai,Yendamuri [22]
;
Annalisa,Guida [23]
;
Michele,Ghidini [24]
;
Nichola O,Awosika [25]
;
Andrea,Napolitano [26]
;
Claudia A M,Fulgenzi [25]
;
Salvatore,Grisanti [27]
;
Francesco,Grossi [28]
;
Armida,D'Incecco [29]
;
Eleni,Josephides [30]
;
Mieke,Van Hemelrijck [31]
;
Alessandro,Russo [32]
;
Alain,Gelibter [33]
;
Gianpaolo,Spinelli [34]
;
Monica,Verrico [35]
;
Bartłomiej,Tomasik [36]
;
Raffaele,Giusti [37]
;
Thomas,Newsom-Davis [38]
;
Emilio,Bria [39]
;
Martin,Sebastian [40]
;
Maximilian,Rost [40]
;
Martin,Forster [41]
;
Uma,Mukherjee [41]
;
Lorenza,Landi [42]
;
Francesca,Mazzoni [43]
;
Avinash,Aujayeb [44]
;
Manuel,Dupont [45]
;
Alessandra,Curioni-Fontecedro [45]
;
Rita,Chiari [46]
;
Francesco,Pantano [3]
;
Alessandro,Morabito [47]
;
Alessandro,Leonetti [48]
;
Alex,Friedlaender [49]
;
Alfredo,Addeo [50]
;
Federica,Zoratto [51]
;
Michele,De Tursi [52]
;
Luca,Cantini [53]
;
Elisa,Roca [54]
;
Giannis,Mountzios [55]
;
Luigi,Della Gravara [56]
;
Sukumar,Kalvapudi [22]
;
Alessandro,Inno [57]
;
Paolo,Bironzo [21]
;
Rafael,Di Marco Barros [30]
;
David,O'Reilly [58]
;
Jack,Bell [58]
;
Eleni,Karapanagiotou [30]
;
Isabelle,Monnet [59]
;
Javier,Baena [60]
;
Marianna,Macerelli [61]
;
Margarita,Majem [62]
;
Francesco,Agustoni [63]
;
Diego Luigi,Cortinovis [64]
;
Giuseppe,Tonini [3]
;
Gabriele,Minuti [42]
;
Chiara,Bennati [65]
;
Laura,Mezquita [66]
;
Teresa,Gorría [66]
;
Alberto,Servetto [67]
;
Teresa,Beninato [68]
;
Giuseppe,Lo Russo [68]
;
Jacobo,Rogado [69]
;
Laura,Moliner [70]
;
Federica,Biello [71]
;
Frank,Aboubakar Nana [72]
;
Anne-Marie,Dingemans [73]
;
Joachim G J V,Aerts [73]
;
Roberto,Ferrara [74]
;
Valter,Torri [75]
;
Taher Abu,Hejleh [76]
;
Kazuki,Takada [77]
;
Abdul Rafeh,Naqash [78]
;
Marina,Garassino [79]
;
Solange,Peters [80]
;
Heather,Wakelee [8]
;
Amin H,Nassar [10]
;
Biagio,Ricciuti [4]
作者单位：
Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy a.cortellini@policlinicocampus.it.;Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, UK.;Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
[1]
Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.;Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, UK.;Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
[2]
Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.;Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
[3]
Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
[4]
Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, UK.;Translational Medicine Department, University of Eastern Piedmont, AOU Maggiore della Carità Hospital, Novara, Italy.
[5]
Department of Oncology, Beaumont Hospital, Beaumont RCSI Cancer Centre, Dublin, Ireland.;RCSI University of Health Sciences, Dublin, Ireland.;Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA.
[6]
Oncology Center, Hospital Sírio-Libanês, Sao Paulo, Sao Paulo, Brazil.
[7]
Department of Medicine Stanford Cancer Institute, Division of Oncology Stanford University, Stanford, California, USA.
[8]
Academic Oncology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
[9]
Section of Medical Oncology, Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut, USA.
[10]
Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
[11]
Medical Thoracic Oncology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
[12]
Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.;Pletonia Institute for Immuno-Oncology, OSUCC - James, The Ohio State University, Columbus, Ohio, USA.
[13]
Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
[14]
Division of Hematology/Oncology/Stem cell transplant, Rush University Medical Center, Chicago, Illinois, USA.
[15]
Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
[16]
Medical Oncology, Versilia Hospital, Azienda USL Toscana Nord Ovest, Lido di Camaiore, Italy.
[17]
Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
[18]
Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, New York, New York, USA.
[19]
Medical Oncology, Santa Maria Della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
[20]
Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, Italy.
[21]
Department of Thoracic Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
[22]
SC Oncologia Medica e Traslazionale, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy.
[23]
Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
[24]
Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, UK.
[25]
Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, UK.
[26]
Department of Medical and Surgical Specialties Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
[27]
Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
[28]
"G Mazzini" Hospital of Teramo, Teramo, Italy.
[29]
Medical Oncology Guy's and St Thomas' Hospitals NHS Trust, London, UK.
[30]
Medical Oncology Guy's and St Thomas' Hospitals NHS Trust, London, UK.;Translational Oncology and Urology Research, King's College London, London, London, UK.
[31]
Medical Oncology Department, Humanitas Istituto Clinico Catanese, Misterbianco, Italy.
[32]
Department of Clinical and Molecular Oncology, "Sapienza" University of Rome, Rome, Italy.
[33]
UOC Territorial Oncology, AUSL Latina (Aprilia), Aprilia, Italy.
[34]
UOC Oncologia A, Department of Hematology, Oncology and Dermatology, Policlinico Umberto I, Rome, Italy.
[35]
Department of Oncology and Radiotherapy, Medical University of Gdańsk, Gdansk, Poland.
[36]
Medical Oncology, Sant'Andrea Hospital, Rome, Italy.
[37]
Department of Oncology and National Centre for HIV Malignancy, Chelsea and Westminster Hospital, London, UK.
[38]
Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.;Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy.
[39]
Department of Medicine II, Hematology/Oncology, University Hospital Frankfurt, Frankfurt, Germany.
[40]
The UCL Cancer Institute, University College London Hospitals NHS Trust, London, UK.
[41]
Clinical Trials Center: Phase 1 and Precision Medicine, IRCCS National Cancer Institute Regina Elena, Rome, Italy.
[42]
Medical Oncology, Careggi University Hospital, Florence, Italy.
[43]
Department of Respiratory Medicine, Northumbria Healthcare NHS Foundation Trust, North Shields, UK.
[44]
Clinic of Oncology, Cantonal Hospital Fribourg, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
[45]
UOC Oncologia, AST Pesaro - Urbino, Pesaro, Italy.
[46]
Thoracic Medical Oncology, Istituto Nazionale Tumori, IRCCS "Fondazione G. Pascale", Naples, Italy.
[47]
Medical Oncology Unit, University Hospital of Parma, Parma, Italy.
[48]
Clinique Générale Beaulieu, Geneva, Switzerland.
[49]
Oncology Service, University Hospital of Geneva, Geneva, Switzerland.
[50]
Ospedale Santa Maria Goretti, Latina, Italy.
[51]
Department of Innovative Technologies in Medicine & Dentistry, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
[52]
Fortrea Inc, Durham, North Carolina, USA.
[53]
Oncologia Toracica - Lung Unit, Ospedale P. Pederzoli, Peschiera del Garda, Italy.
[54]
4th Department of Medical Oncology and Clinical Trials Unit, Henry Dunant Hospital Center, Athens, Greece.
[55]
Department of Pulmonary Oncology, AORN dei Colli Monaldi, Naples, Italy.
[56]
Medical Oncology Unit, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Italy.
[57]
Department of Oncology, Beaumont Hospital, Beaumont RCSI Cancer Centre, Dublin, Ireland.
[58]
Service de Pneumologie, Centre Hospitalier Intercommunal, Creteil, France.
[59]
Hospital Universitario 12 de Octubre, Madrid, Spain.
[60]
Department of Oncology, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Udine, Italy.
[61]
Department of Medical Oncology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain.
[62]
Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
[63]
Division of Medical Oncology, Fondazione IRCCS San Gerardo dei Tintori di Monza, Monza, Italy.;Department of Clinical Medicine, University of Milano-Bicocca, Monza, Italy.
[64]
Department of Onco-Hematology, AUSL della Romagna, Ravenna, Italy.
[65]
Medical Oncology Department, Hospital Clinic of Barcelona, Barcelona, Spain.
[66]
Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
[67]
Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
[68]
Medical Oncology Department, Hospital Universitario Infanta Lenor, Madrid, Spain.
[69]
Department of Medical Oncology, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain.
[70]
Translational Medicine Department, University of Eastern Piedmont, AOU Maggiore della Carità Hospital, Novara, Italy.
[71]
Division of Pneumology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
[72]
Department of Pulmonary Medicine, Erasmus MC Cancer Institute University Medical Center, Rotterdam, Netherlands.
[73]
Università Vita-Salute San Raffaele, Milan, Italy.;Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.
[74]
Department of Clinical Oncology, "Mario Negri" Institute for Pharmacological Research- IRCCS, Milan, Italy.
[75]
Department of Internal Medicine, Medical Oncology, King Hussein Cancer Center, Amman, Jordan.;Department of Internal Medicine, Hematology, Oncology and Blood and Marrow Transplantation, University of Iowa, Iowa City, Lowa, USA.
[76]
Department of Surgery, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
[77]
Medical Oncology/TSET Phase 1 Program, The University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, USA.
[78]
Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois, USA.
[79]
Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland.
[80]
医学主题词
人类(Humans);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);男(雄)性(Male);女(雌)性(Female);肺肿瘤(Lung Neoplasms);中年人(Middle Aged);老年人(Aged);登记(Registries);老年人, 80以上(Aged, 80 and over)
DOI
10.1136/jitc-2024-010674
PMID
39904562
发布时间
2025-06-12
- 浏览0
Journal for immunotherapy of cancer
Journal for immunotherapy of cancer
2025年13卷2期
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