Silencing LINC01547 induces hepatocellular carcinoma cell apoptosis and metastasis inhibition via the ADAR1/FAK and miR-146b-5p/RAC1 axes.

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第一作者： Dan,Wang

第一单位： Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China.

作者： Dan,Wang ^[1] ; Huijie,Zhao ^[2] ; Ying,Zhao ^[2] ; Xuejing,An ^[2] ; Chuanqin,Shi ^[3] ; Zhaohai,Pan ^[2] ; Qiusheng,Zheng ^[2] ; Xin,Wang ^[4] ; Jun,Lu ^[5] ; Defang,Li ^[6]

作者单位： Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China. ^[1] Featured Laboratory for Biosynthesis and Target Discovery of Active Components of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, Shandong, 264003, PR China. ^[2] Center of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, 255020, PR China. ^[3] Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China. xinwangPharm@hainanu.edu.cn.;Key Laboratory of Tropical Biological Resources of Ministry of Education and One Health Institute, School of Pharmaceutical Sciences, Hainan University, Haikou, 570228, PR China. xinwangPharm@hainanu.edu.cn. ^[4] State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China. ljaaa111@163.com. ^[5] Featured Laboratory for Biosynthesis and Target Discovery of Active Components of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, Shandong, 264003, PR China. lidefang@163.com.;College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China. lidefang@163.com. ^[6]

关键词 ADAR1/FAK Apoptosis Hepatocellular carcinoma LINC01547 Metastasis miR-146b-5p/RAC1

DOI 10.1007/s10495-024-02070-0

PMID 39904859

发布时间 2025-02-04

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Silencing LINC01547 induces hepatocellular carcinoma cell apoptosis and metastasis inhibition via the ADAR1/FAK and miR-146b-5p/RAC1 axes.

Apoptosis

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Apoptosis

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Silencing LINC01547 induces hepatocellular carcinoma cell apoptosis and metastasis inhibition via the ADAR1/FAK and miR-146b-5p/RAC1 axes.

Apoptosis

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Apoptosis

相关期刊

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