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首页> Frontiers in immunology> DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells.

DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells.

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作者： Maria Cristina,Grimaldi ^[1] ; Sara,Bozzer ^[2] ; Dick J,Sjöström ^[3] ; Linnea I,Andersson ^[4] ; Tom Eirik,Mollnes ^[5] ; Per H,Nilsson ^[3] ; Luca,De Maso ^[1] ; Federico,Riccardi ^[2] ; Michele,Dal Bo ^[2] ; Daniele,Sblattero ^[1] ; Paolo,Macor ^[1]

作者单位： Department of Life Sciences, University of Trieste, Trieste, Italy. ^[1] Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy. ^[2] Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden.;Department of Chemistry and Biomedical Sciences, Linnaeus University, Kalmar, Sweden. ^[3] Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden. ^[4] Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway.;Research Laboratory, Nordland Hospital, Bodo, Norway. ^[5]

关键词 in vivo transfection polymeric nanoparticles safety targeting zebrafish

主题词人类(Humans);动物(Animals);纳米粒子(Nanoparticles);DNA(DNA);细胞系, 肿瘤(Cell Line, Tumor);绿色荧光蛋白质类(Green Fluorescent Proteins);聚乙烯乙醇(Polyvinyl Alcohol);B-淋巴细胞(B-Lymphocytes);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);基因转移技术(Gene Transfer Techniques)

DOI 10.3389/fimmu.2024.1509322

PMID 39911576

发布时间 2025-02-07

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