换一批
换一批Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress.
第一作者：
Tingting,Fang
第一单位：
Department of Pathophysiology, College of Basic Medical Science, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning, China.
作者：
主题词
动物(Animals);氧化性应激(Oxidative Stress);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);糖尿病心肌病(Diabetic Cardiomyopathies);肌细胞, 心脏(Myocytes, Cardiac);糖尿病, 实验性(Diabetes Mellitus, Experimental);男(雄)性(Male);信号传导(Signal Transduction);线粒体, 心脏(Mitochondria, Heart);增量调节(Up-Regulation);小鼠, 近交C57BL(Mice, Inbred C57BL);甘氨酸(Glycine);异喹啉类(Isoquinolines);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);苯并二恶茂类(Benzodioxoles);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);NF-E2相关因子2(NF-E2-Related Factor 2);细胞, 培养的(Cells, Cultured);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷酸肌醇3-激酶(Phosphatidylinositol 3-Kinase);小鼠(Mice);大鼠(Rats)
DOI
10.1186/s12933-025-02601-2
PMID
39920720
发布时间
2025-02-10
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