作者:
Siavash,Raeisi Dehkordi [1]
;
Ivy Tsz-Lo,Wong [2]
;
Jing,Ni [3]
;
Jens,Luebeck [1]
;
Kaiyuan,Zhu [1]
;
Gino,Prasad [1]
;
Lena,Krockenberger [1]
;
Guanghui,Xu [4]
;
Biswanath,Chowdhury [1]
;
Utkrisht,Rajkumar [1]
;
Ann,Caplin [1]
;
Daniel,Muliaditan [5]
;
Aditi,Gnanasekar [2]
;
Ceyda,Coruh [6]
;
Qiushi,Jin [7]
;
Kristen,Turner [8]
;
Shu Xian,Teo [9]
;
Andy Wing Chun,Pang [10]
;
Ludmil B,Alexandrov [11]
;
Christelle En Lin,Chua [9]
;
Frank B,Furnari [12]
;
John,Maciejowski [13]
;
Thomas G,Paulson [14]
;
Julie A,Law [15]
;
Howard Y,Chang [16]
;
Feng,Yue [17]
;
Ramanuj,DasGupta [18]
;
Jean,Zhao [19]
;
Paul S,Mischel [20]
;
Vineet,Bafna [21]
作者单位:
Department of Computer Science and Engineering, University of California San Diego, San Diego, CA, USA.
[1]
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.;Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
[2]
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.;Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
[3]
Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
[4]
Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore, 138672, Republic of Singapore.
[5]
Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.;ClearNote Health, San Diego, CA, 92121, USA.
[6]
Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
[7]
Boundless Bio, San Diego, CA, USA.
[8]
Singapore Nuclear Research and Safety Initiative, National University of Singapore, Singapore, 138672, Republic of Singapore.
[9]
Bionano Genomics, San Diego, CA92121, USA.
[10]
Moores Cancer Center, UC San Diego Health, La Jolla, CA, USA.;Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.;Department of Bioengineering, University of California at San Diego, La Jolla, CA, USA.
[11]
Department of Medicine, University of California at San Diego, La Jolla, CA, USA.
[12]
Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[13]
Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
[14]
Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.;Division of Biological Sciences, University of California, San Diego, La Jolla, CA, 92093, USA.
[15]
Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.;Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
[16]
Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.;Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA.
[17]
Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore, 138672, Republic of Singapore.;School of Cancer Sciences, University of Glasgow; Senior Group Leader, CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
[18]
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. Jean_Zhao@dfci.harvard.edu.;Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA. Jean_Zhao@dfci.harvard.edu.
[19]
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. pmischel@stanford.edu.;Sarafan ChEM-H, Stanford University, Stanford, CA, USA. pmischel@stanford.edu.
[20]
Department of Computer Science and Engineering, University of California San Diego, San Diego, CA, USA. vbafna@ucsd.edu.;Halıcıoğlu Data Science Institute, University of California at San Diego, La Jolla, CA, USA. vbafna@ucsd.edu.
[21]
主题词
人类(Humans);癌基因(Oncogenes);细胞系, 肿瘤(Cell Line, Tumor);基因扩增(Gene Amplification);肿瘤(Neoplasms);动物(Animals);小鼠(Mice);算法(Algorithms);遗传异质性(Genetic Heterogeneity)
DOI
10.1038/s41467-025-56670-8
PMID
39929823
发布时间
2025-02-13
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