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Genetic architecture in Greenland is shaped by demography, structure and selection.

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作者单位: Department of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark. [1] Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [2] Department of Internal Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.;Department of Clinical Medicine, Arctic Health Research Centre, Aalborg University Hospital, Aalborg, Denmark. [3] Ilisimatusarfik - University of Greenland, Nuuk, Greenland. [4] Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK.;Nuffield Department of Population Health, University of Oxford, Oxford, UK. [5] Centre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.;Greenland Center for Health Research, Institute for Health and Nature, University of Greenland, Nuuk, Greenland. [6] Centre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark. [7] Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark.;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [8] Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.;TUM School of Medicine and Heath, Technical University of Munich (TUM) and Klinikum Rechts der Isar, Munich, Germany. [9] Departments of Integrative Biology and Statistics, University of California at Berkeley, California, CA, USA.;GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. [10] Centre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.;Greenland Center for Health Research, Institute for Health and Nature, University of Greenland, Nuuk, Greenland.;Steno Diabetes Center Greenland, Nuuk, Greenland. [11] Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. torben.hansen@sund.ku.dk. [12] Department of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark. ida@bio.ku.dk. [13] Department of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark. aalbrechtsen@bio.ku.dk. [14]
DOI 10.1038/s41586-024-08516-4
PMID 39939757
发布时间 2025-02-12
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