Optimization of CRISPR/Cas9 Gene Editing System in Sheep (<i>Ovis aries</i>) Oocytes via Microinjection.

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第一作者： Haitao,Wang

第一单位： State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

作者： Haitao,Wang ^[1] ; Hengqian,Yang ^[2] ; Tingting,Li ^[1] ; Yan,Chen ^[1] ; Jieran,Chen ^[1] ; Xiaosheng,Zhang ^[3] ; Jinlong,Zhang ^[3] ; Yuting,Zhang ^[1] ; Na,Zhang ^[1] ; Runlin,Ma ^[1] ; Xun,Huang ^[1] ; Qiuyue,Liu ^[1]

作者单位： State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. ^[1] State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.;College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China. ^[2] Institute of Animal Sciences and Veterinary, Tianjin Academy of Agriculture Sciences, Tianjin 300381, China.;Tianjin Key Laboratory of Animal Molecular Breeding and Biotechnology, Tianjin 300381, China. ^[3]

关键词 CRISPR/Cas9 gene editing microinjection sheep

主题词动物(Animals);卵母细胞(Oocytes);微量注射(Microinjections);绵羊(Sheep);女(雌)性(Female);细胞因子信号转导蛋白抑制因子(Suppressor of Cytokine Signaling Proteins)

DOI 10.3390/ijms26031065

PMID 39940839

发布时间 2025-02-13

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