Targeted delivery of Grem1 and IL-10 separately by mesenchymal stem cells effectively mitigates SETD2-deficient inflammatory bowel disease.
第一作者:
Rebiguli,Aji
第一单位:
State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.;School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
作者:
主题词
动物(Animals);炎性肠疾病(Inflammatory Bowel Diseases);间质干细胞(Mesenchymal Stem Cells);小鼠(Mice);白细胞介素10(Interleukin-10);疾病模型, 动物(Disease Models, Animal);硫酸葡聚糖(Dextran Sulfate);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);结肠炎(Colitis);间质干细胞移植(Mesenchymal Stem Cell Transplantation);人类(Humans);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);小鼠, 近交C57BL(Mice, Inbred C57BL)
DOI
10.7150/thno.105876
PMID
39990215
发布时间
2025-02-25
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Theranostics
2215-2228页
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