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Assessing the clinical applicability of dimensionality reduction algorithms in flow cytometry for hematologic malignancies.

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第一作者： Min-Seung,Park

第一单位： Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

作者： Min-Seung,Park ^[1] ; Jong Kwon,Lee ^[2] ; Boram,Kim ^[2] ; Hee Young,Ju ^[3] ; Keon Hee,Yoo ^[3] ; Chul Won,Jung ^[4] ; Hee-Jin,Kim ^[2] ; Hyun-Young,Kim ^[2]

作者单位： Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. ^[1] Department of Laboratory Medicine and Genetics, 36626 Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea. ^[2] Department of Pediatrics, 36626 Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea. ^[3] Division of Hematology-Oncology, Department of Medicine, 36626 Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea. ^[4]

关键词 dimensionality reduction flow cytometry hematologic malignancy t-distributed stochastic neighbor embedding (t-SNE)uniform manifold approximation and projection (UMAP)

主题词人类(Humans);流式细胞术(Flow Cytometry);算法(Algorithms);血液肿瘤(Hematologic Neoplasms);多发性骨髓瘤(Multiple Myeloma);肿瘤, 残余(Neoplasm, Residual)

DOI 10.1515/cclm-2025-0017

PMID 40009469

发布时间 2025-05-28

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