首页> Journal of anaesthesiology, clinical pharmacology> Impact of anesthetic induction with etomidate, thiopentone, and propofol on regional cerebral oxygenation: An observational study in patients with traumatic brain injury.

Impact of anesthetic induction with etomidate, thiopentone, and propofol on regional cerebral oxygenation: An observational study in patients with traumatic brain injury.

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第一作者： Kunal K,Sharma

第一单位： Department of Neruroanesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

作者： Kunal K,Sharma ^[1] ; Rohini M,Surve ^[1] ; K R Madhusudan,Reddy ^[1] ; Rita,Christopher ^[2] ; Dhritiman,Chakrabarti ^[1] ; Sundaravadivel,Pandarisamy ^[2] ; Shruti V,Palakuzhiyil ^[2] ; Sriganesh,Kamath ^[1]

作者单位： Department of Neruroanesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India. ^[1] Department of Neurovirology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India. ^[2]

关键词 Blood pressure Key Messages: Anesthetic induction with etomidate produced least hemodynamic changes compared to induction with thiopentone and propofol in patients with traumatic brain injury. Consequently, maximal increase in cerebral oxygen saturation occurred with etomidate among the three induction agents. An insignificant decrease in serum cortisol was observed with etomidate and thiopentone, but not with propofol. Neurological outcome at discharge was similar with all drugs.cerebral oxygen saturation cortisol etomidate propofol thiopentone traumatic brain injury

DOI 10.4103/joacp.joacp_315_23

PMID 40026717

发布时间 2025-03-04

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