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A high-throughput screening platform to identify <i>MYCN</i> expression inhibitors for liver cancer therapy.

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第一作者： Yali,Xu

第一单位： Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Kanagawa, Yokohama, Japan.;Department of Intensive Care Unit, The Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.

作者： Yali,Xu ^[1] ; Hricha,Mishra ^[2] ; Yutaka,Furutani ^[3] ; Kaori,Yanaka ^[3] ; Hajime,Nishimura ^[2] ; Erina,Furuhata ^[2] ; Masataka,Takahashi ^[2] ; Luc,Gailhouste ^[4] ; Yusuke,Suenaga ^[5] ; Yoshitaka,Hippo ^[5] ; Wenkui,Yu ^[6] ; Tomokazu,Matsuura ^[3] ; Harukazu,Suzuki ^[2] ; Xian-Yang,Qin ^[2]

作者单位： Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Kanagawa, Yokohama, Japan.;Department of Intensive Care Unit, The Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China. ^[1] Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Kanagawa, Yokohama, Japan. ^[2] Department of Laboratory Medicine, The Jikei University School of Medicine, Tokyo, Japan. ^[3] Laboratory for Brain Development and Disorders, RIKEN Center for Brain Science, Saitama, Japan. ^[4] Laboratory of Evolutionary Oncology, Chiba Cancer Center Research Institute, Chiba, Japan. ^[5] Department of Intensive Care Unit, The Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China. ^[6]

关键词 Acot2 DDI core library MYCN gRNA library high-throughput screening liver cancer

DOI 10.3389/fonc.2025.1486671

PMID 40027135

发布时间 2025-03-04

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