换一批VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway.
第一作者：
Honglan,Sun
第一单位：
Key Laboratory of Emergency and Trauma of Ministry of Education, Department of Stomatology, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Clinical College/First Affiliated Hospital, Hainan Medical University, Haikou City, 570102, Hainan Province, China.;School of Stomatology, Hainan Medical University, Haikou City, 571199, Hainan Province, China.
作者：
医学主题词
人类(Humans);口腔黏膜下纤维化(Oral Submucous Fibrosis);脑视网膜血管瘤抑制蛋白质(Von Hippel-Lindau Tumor Suppressor Protein);槟榔碱(Arecoline);信号传导(Signal Transduction);NF-κB(NF-kappa B);泛素化(Ubiquitination);口腔黏膜(Mouth Mucosa);成纤维细胞(Fibroblasts)
DOI
10.1038/s41598-025-91207-5
PMID
40038412
发布时间
2025-05-10
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