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Active Cryptococcus neoformans glucuronoxylomannan production prevents elimination of cryptococcal CNS infection in vivo.

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第一作者： Vanessa,Enriquez

第一单位： Department of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, DG-48, P.O. Box 100424, Gainesville, FL, 32610, USA.

作者： Vanessa,Enriquez ^[1] ; Melissa E,Munzen ^[1] ; Luz M,Porras ^[2] ; Claudia L,Charles-Niño ^[1] ; Fahong,Yu ^[3] ; Karina,Alviña ^[4] ; Raddy L,Ramos ^[5] ; Michael R,Dores ^[6] ; Paola,Giusti-Rodriguez ^[7] ; Luis R,Martinez ^[8]

作者单位： Department of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, DG-48, P.O. Box 100424, Gainesville, FL, 32610, USA. ^[1] Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA. ^[2] Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, USA. ^[3] Department of Neuroscience, University of Florida College of Medicine, Gainesville, FL, USA.;Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, USA.;McKnight Brain Institute, University of Florida, Gainesville, FL, USA. ^[4] Department of Biomedical Sciences, NYIT College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY, USA. ^[5] Department of Biology, Hofstra University, Hempstead, NY, USA. ^[6] Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA.;McKnight Brain Institute, University of Florida, Gainesville, FL, USA. ^[7] Department of Oral Biology, University of Florida College of Dentistry, 1395 Center Drive, DG-48, P.O. Box 100424, Gainesville, FL, 32610, USA. LMartinez@dental.ufl.edu.;Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, USA. LMartinez@dental.ufl.edu.;McKnight Brain Institute, University of Florida, Gainesville, FL, USA. LMartinez@dental.ufl.edu.;Center for Immunology and Transplantation, University of Florida, Gainesville, FL, USA. LMartinez@dental.ufl.edu.;Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. LMartinez@dental.ufl.edu. ^[8]

关键词 C. neoformans Cryptococcoma Meningoencephalitis Microglia Phagocytosis