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Fibroblast-based radiosensitivity assays as a clinically valuable tool for (severe) combined immunodeficiency syndromes.

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第一作者： Elien,Beyls

第一单位： Primary Immunodeficiency Research Lab (PIRL), Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium. Electronic address: Elien.Beyls@UGent.be.

作者： Elien,Beyls ^[1] ; Somara,De Beul ^[2] ; Victoria,Bordon ^[3] ; Alina,Ferster ^[4] ; Filomeen,Haerynck ^[5] ; Anne,Vral ^[6] ; Ans,Baeyens ^[6]

作者单位： Primary Immunodeficiency Research Lab (PIRL), Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium. Electronic address: Elien.Beyls@UGent.be. ^[1] Radiobiology Lab, Department of Human Structure and Repair, Ghent University, Ghent, Belgium. ^[2] Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium. ^[3] Pediatric Hematology, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium. ^[4] Primary Immunodeficiency Research Lab (PIRL), Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium. ^[5] Radiobiology Lab, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent 9000, Belgium. ^[6]

关键词 Fibroblasts Immunodeficiency Micronucleus assay Radiosensitivity γH2AX focus assay