首页> Phytomedicine : international journal of phytotherapy and phytopharmacology> Alkannin triggered apoptosis and ferroptosis in gastric cancer by suppressing lipid metabolism mediated by the c-Fos/SREBF1 axis.

Alkannin triggered apoptosis and ferroptosis in gastric cancer by suppressing lipid metabolism mediated by the c-Fos/SREBF1 axis.

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第一作者： Huayang,Yu

第一单位： Division of Abdominal Tumor Multimodality Treatment, Cancer Center and Lab of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China.

作者： Huayang,Yu ^[1] ; Qiming,Kou ^[1] ; Hang,Yuan ^[1] ; Yanyu,Qi ^[2] ; Qin,Li ^[1] ; Liang,Li ^[1] ; Gang,Zhao ^[1] ; Guanru,Wang ^[1] ; Siqi,Li ^[1] ; Jie,Qu ^[1] ; Hongbai,Chen ^[1] ; Minghui,Zhao ^[1] ; Qijing,Wang ^[1] ; Shan,Li ^[1] ; Kang,Chen ^[1] ; Chenghong,Lu ^[1] ; Hengyi,Xiao ^[3] ; Ping,Lin ^[4] ; Kai,Li ^[5]

作者单位： Division of Abdominal Tumor Multimodality Treatment, Cancer Center and Lab of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China. ^[1] Department of Oncology, Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Sichuan Chengdu 610404, PR China. ^[2] Division of Abdominal Tumor Multimodality Treatment, Cancer Center and Lab of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China. Electronic address: hengyix@scu.edu.cn. ^[3] Division of Abdominal Tumor Multimodality Treatment, Cancer Center and Lab of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China. Electronic address: linping@scu.edu.cn. ^[4] Division of Abdominal Tumor Multimodality Treatment, Cancer Center and Lab of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China. Electronic address: likai@scu.edu.cn. ^[5]

关键词 Alkannin C-Fos Ferroptosis Gastric cancer Lipid metabolism SREBF1 Transcriptional activation