Neuroprotective effects of hirudin against cerebral ischemia-reperfusion injury via inhibition of CCL2-mediated ferroptosis and inflammatory pathways.
第一作者:
Junbao,Liao
第一单位:
Department of Cerebrovascular Disease, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, PR China.
作者:
主题词
动物(Animals);趋化因子CCL2(Chemokine CCL2);再灌注损伤(Reperfusion Injury);水蛭素类(Hirudins);小鼠(Mice);神经保护药(Neuroprotective Agents);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);信号传导(Signal Transduction);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);脑缺血(Brain Ischemia);神经元(Neurons);炎症(Inflammation);氧化性应激(Oxidative Stress)
DOI
10.1016/j.brainresbull.2025.111293
PMID
40064243
发布时间
2025-04-13
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Brain research bulletin
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