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Invasive Salmonella Typhimurium colonizes gallbladder and contributes to gallbladder carcinogenesis through activation of host epigenetic modulator KDM6B.

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第一作者： Agila Kumari,Pragasam

第一单位： Functional Genomics Laboratory, Centre for Microbial Research, BRIC-Translational Health Science and Technology Institute, Faridabad, 121001, India.

作者： Agila Kumari,Pragasam ^[1] ; Sonalika,Maurya ^[2] ; Kajal,Jain ^[3] ; Sujoy,Pal ^[4] ; Christu,Raja ^[5] ; Rajni,Yadav ^[6] ; Shakti,Kumar ^[1] ; Ayushi,Purohit ^[1] ; Dibyabhaba,Pradhan ^[5] ; Kirti,Kajal ^[2] ; Daizee,Talukdar ^[1] ; Anand Narayan,Singh ^[4] ; Jyoti,Verma ^[1] ; Pradipta,Jana ^[1] ; Shefali,Rawat ^[6] ; Pallavi,Kshetrapal ^[7] ; Asuri,Krishna ^[5] ; Subodh,Kumar ^[8] ; Virinder Kumar,Bansal ^[5] ; Bhabatosh,Das ^[9] ; Chittur V,Srikanth ^[10] ; Pramod Kumar,Garg ^[11]

作者单位： Functional Genomics Laboratory, Centre for Microbial Research, BRIC-Translational Health Science and Technology Institute, Faridabad, 121001, India. ^[1] Laboratory of Gut Infection and Inflammation Biology, Regional Centre for Biotechnology, Faridabad, 121001, India. ^[2] Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India. ^[3] Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India. ^[4] Centralized Core Research Facility, All India Institute of Medical Sciences, New Delhi, 110029, India. ^[5] Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India. ^[6] Pediatric Biology Center, BRIC-Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[7] Department of Surgery, JPN Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, 110029, India. ^[8] Functional Genomics Laboratory, Centre for Microbial Research, BRIC-Translational Health Science and Technology Institute, Faridabad, 121001, India. Electronic address: bhabatosh@thsti.res.in. ^[9] Laboratory of Gut Infection and Inflammation Biology, Regional Centre for Biotechnology, Faridabad, 121001, India. Electronic address: cvsrikanth@rcb.res.in. ^[10] Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, 110029, India. Electronic address: pgarg@aiims.edu. ^[11]

关键词 Gallbladder cancer Gallstones Inflammation KDM6B Microbiome Salmonella