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Decreased dihydroartemisinin-piperaquine protection against recurrent malaria associated with Plasmodium falciparum plasmepsin 3 copy number variation in Africa.

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第一作者: Leyre,Pernaute-Lau
第一单位: Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden.;BioISI - Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon, Lisbon, Portugal.;The Art of Discovery, Derio, Basque Country, Spain.
作者单位: Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden.;BioISI - Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon, Lisbon, Portugal.;The Art of Discovery, Derio, Basque Country, Spain. [1] Centre for Ecology and Conservation, University of Exeter, Penryn Campus, Penryn, UK.;Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany. [2] Malaria Research and Training Center, Faculty of Pharmacy, University of Science, Techniques and Technologies of Bamako, Bamako, Mali.;Dept. of Clinical Pharmacology, University of Heidelberg, Heidelberg, Germany. [3] Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden.;Molecular Biology and Malaria Immunology Research Group, Instituto René Rachou, Fundação Oswaldo Cruz (FIOCRUZ); Belo, Horizonte, Brasil. [4] Malaria Research and Training Center, Faculty of Pharmacy, University of Science, Techniques and Technologies of Bamako, Bamako, Mali. [5] Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden. [6] Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany. [7] Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, Braga, Portugal.;ICVS/3B's─PT Government Associate Laboratory; 4806-909 Guimarães, Braga, Portugal. [8] German Center for Infection Research (DZIF), Tübingen, Germany. [9] Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden.;Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. [10] Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany.;German Center for Infection Research (DZIF), Tübingen, Germany.;Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon. [11] Department of Microbiology and Tumour Cell Biology, Karolinska Institutet, Stockholm, Sweden. jose.pedro.gil@ki.se.;Clinical Tropical Medicine (CTM), Global Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, Nova University of Lisbon, Lisbon, Portugal. jose.pedro.gil@ki.se. [12]
DOI 10.1038/s41467-025-57726-5
PMID 40102390
发布时间 2025-05-30
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