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CCL19/MIP-3β as a key mediator in the production of anti-GPIIb/IIIa antibody-producing B cells in patients with chronic hepatitis C.

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第一作者： Junki,Iida

第一单位： Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

作者： Junki,Iida ^[1] ; Haruki,Uojima ^[2] ; Takashi,Satoh ^[3] ; Masaya,Sugiyama ^[4] ; Akira,Take ^[5] ; Yoshihiko,Sakaguchi ^[6] ; Kazuyoshi,Gotoh ^[7] ; Hisashi,Hidaka ^[1] ; Shunji,Hayashi ^[5] ; Yasuhito,Tanaka ^[8] ; Makoto,Otsu ^[9] ; Chika,Kusano ^[1]

作者单位： Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. ^[1] Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; Genome Medical Sciences Project, Research Institute, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan. Electronic address: kiruha@kitasato-u.ac.jp. ^[2] Division of Hematology, Kitasato University School of Allied Health Sciences, Sagamihara, Kanagawa, Japan; Regenerative Medicine and Cell Design Research Facility, Kitasato University School of Allied Health Sciences, Sagamihara, Kanagawa, Japan. Electronic address: takashis@kitasato-u.ac.jp. ^[3] Department of Viral Pathogenesis and Controls, Research Institute, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan. ^[4] Department of Microbiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. ^[5] Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, Japan. ^[6] Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. ^[7] Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. ^[8] Division of Hematology, Kitasato University School of Allied Health Sciences, Sagamihara, Kanagawa, Japan. ^[9]

关键词 Anti-GPIIb/IIIa antibody-producing B cells C-C motif chemokine ligand 19 (CCL19/MIP-3β)Chronic liver disease Direct-acting antiviral therapy Thrombocytopenia