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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.

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第一作者: Isidoro,Cobo
第一单位: Division of Clinical Immunology & Rheumatology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; CAMBAC (Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center), University of Alabama at Birmingham, Birmingham, CA, USA. Electronic address: isidorocobo@uabmc.edu.
作者单位: Division of Clinical Immunology & Rheumatology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; CAMBAC (Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center), University of Alabama at Birmingham, Birmingham, CA, USA. Electronic address: isidorocobo@uabmc.edu. [1] Division of Rheumatology, Allergy, and Immunology, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, San Diego, CA, USA. [2] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, San Diego, CA, USA. [3] Division of Clinical Immunology & Rheumatology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. [4] Department of Medicine, University of California, San Diego, La Jolla, San Diego, CA, USA. [5] VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. [6] Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. [7] Center for Pathobiochemistry & Genetics, Medical University of Vienna, Vienna, Austria. [8] Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; CIBER en Enfermedades Cardiovasculares (CIBER-CV), Madrid, Spain. [9] Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. [10] Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA; Division of Cardiology, Pittsburgh VA Medical Center, Pittsburgh, PA, USA. [11] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Howard Hughes Medical Institute, Boston, MA, USA. [12] Department of Physiology, Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. [13] Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA 92093, USA. [14] Division of Rheumatology, Allergy, and Immunology, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, San Diego, CA, USA; Department of Medicine, Autonomous University of Barcelona, Plaça Cívica, Bellaterra, Barcelona 08193, Spain. [15] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, San Diego, CA, USA. Electronic address: cglass@health.ucsd.edu. [16]
DOI 10.1016/j.immuni.2025.02.023
PMID 40118070
发布时间 2026-04-09
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Immunity

Immunity

2025年58卷4期

826-842.e8页

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