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Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA.

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第一作者： Yuhang,Fan

第一单位： Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

作者： Yuhang,Fan ^[1] ; Wenchao,Xu ^[1] ; Bao-Qing,Gao ^[2] ; Huichao,Qin ^[1] ; Xiaoyi,Wu ^[1] ; Jia,Wei ^[3] ; Qingyang,Ni ^[1] ; Lina,Zhou ^[1] ; Jiangchao,Xiang ^[1] ; Jing,Wu ^[1] ; Bei,Yang ^[4] ; Li,Yang ^[3] ; Jia,Chen ^[5]

作者单位： Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China. ^[1] Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.;Center for Molecular Medicine, Children's Hospital of Fudan University and Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. ^[2] Center for Molecular Medicine, Children's Hospital of Fudan University and Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. ^[3] Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.;Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.;Shanghai Clinical Research and Trial Center, Shanghai, China. ^[4] Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China. chenjia@shanghaitech.edu.cn.;Shanghai Clinical Research and Trial Center, Shanghai, China. chenjia@shanghaitech.edu.cn. ^[5]