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Design and delivery effect of prolonged-retention dexamethasone and tacrolimus microcrystals eye drops.

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第一作者： Ji,Huang

第一单位： Guangdong Provincial Key Laboratory for Research and Evaluation of Pharmaceutical Preparations, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China.

作者： Ji,Huang ^[1] ; Siying,Yuan ^[1] ; Jinlan,Mao ^[1] ; Kangyiran,Pan ^[1] ; Li,Liu ^[2] ; Ilva D,Rupenthal ^[3] ; Qinqiang,Long ^[4] ; Lin,He ^[5] ; Qinyu,Li ^[1] ; Lirong,Guo ^[1] ; Suling,Bei ^[1] ; Tianying,Huang ^[1] ; Xifeng,Teng ^[6] ; Xiao,Yu ^[7] ; Dongzhi,Hou ^[8]

作者单位： Guangdong Provincial Key Laboratory for Research and Evaluation of Pharmaceutical Preparations, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. ^[1] Guangzhou Huangpu District New Drug Application Service Center, Guangzhou 510663, PR China. ^[2] Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. ^[3] Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. ^[4] Teaching and Experimental Center, Guangdong Pharmaceutical University, Zhongshan 528458, PR China. ^[5] College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. Electronic address: tengxifeng@gdpu.edu.cn. ^[6] Guangdong Provincial Key Laboratory for Research and Evaluation of Pharmaceutical Preparations, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. Electronic address: yuxiao@gdpu.edu.cn. ^[7] Guangdong Provincial Key Laboratory for Research and Evaluation of Pharmaceutical Preparations, College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. Electronic address: houdongzhi406@163.com. ^[8]

关键词 Acute conjunctivitis Dexamethasone Dry eye Layer-by-layer self-assembly Microcrystals Tacrolimus