Selenium supplementation protects cancer cells from the oxidative stress and cytotoxicity induced by the combination of ascorbate and menadione sodium bisulfite.

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第一作者： Radosveta,Gencheva

第一单位： Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 17177, Sweden.

作者： Radosveta,Gencheva ^[1] ; Lucia,Coppo ^[1] ; Elias S J,Arnér ^[2] ; Xiaoyuan,Ren ^[3]

作者单位： Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 17177, Sweden. ^[1] Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 17177, Sweden; Department of Selenoprotein Research, National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary. ^[2] Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 17177, Sweden; IC-MedTech Corporation, Las Vegas, NV, USA. Electronic address: xiaoyuan.ren@ki.se. ^[3]

关键词 Ascorbate Cancer Hydrogen peroxide Menadione sodium bisulfite Oxidative stress Selenium Selenoproteins

DOI 10.1016/j.freeradbiomed.2025.03.049

PMID 40180024

发布时间 2025-04-10

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