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Short-chain fatty acids alleviate cholestatic liver injury by improving gut microbiota and bile acid metabolism.

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第一作者： Han,Lu

第一单位： The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210003, China; Huadong Medical Institute of Biotechniques, Nanjing 210018, China.

作者： Han,Lu ^[1] ; Mingmin,Zhang ^[2] ; Yanan,Hu ^[3] ; Xuewei,Sun ^[4] ; Ruonan,Zhang ^[5] ; Xinrui,Zhang ^[6] ; Mingyan,Zhang ^[7] ; Chengliang,Tang ^[4] ; Qian,Cui ^[8] ; Zhuohan,Zhang ^[4] ; Zihan,Wu ^[4] ; Wenjing,Wang ^[9] ; Shuang,Song ^[9] ; Lunbiao,Cui ^[10] ; Jin,Zhu ^[4] ; Xiaojun,Yang ^[11] ; Zhan,Yang ^[12]

作者单位： The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210003, China; Huadong Medical Institute of Biotechniques, Nanjing 210018, China. ^[1] Ili & Jiangsu Joint Institute of Health, Ili 835000, China; The Friendship Hospital of Ili Kazakh Autonomous Prefecture, Ili 835000, China. ^[2] The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing 211800, China. ^[3] Huadong Medical Institute of Biotechniques, Nanjing 210018, China. ^[4] Department of Pathogen Biology, Nanjing Medical University, Nanjing 211100, China. ^[5] School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210046, China. ^[6] Jinling Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210046, China. ^[7] Air Force Hospital of Eastern Theater, Nanjing 210008, China. ^[8] Department of Infectious Disease, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China. ^[9] NHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Medical Key Laboratory of Pathogenic Microbiology in Emerging Major Infectious Diseases, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China. ^[10] The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210003, China. Electronic address: yangxiaojunvip@163.com. ^[11] Huadong Medical Institute of Biotechniques, Nanjing 210018, China. Electronic address: breezezhan@126.com. ^[12]

关键词 Akkermansia muciniphila Bile acids metabolism Cholestasis Gut microbiome Short-chain fatty acids α-Naphthylisothiocyanate