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scAMZI: attention-based deep autoencoder with zero-inflated layer for clustering scRNA-seq data.

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第一作者： Lin,Yuan

第一单位： Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), 3501 Daxue Road, Jinan, 250353, China.;Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), 3501 Daxue Road, Jinan, 250353, China.;Shandong Provincial Key Laboratory of Industrial Network and Information System Security, Shandong Fundamental Research Center for Computer Science, 3501 Daxue Road, Jinan, 250353, China.

作者： Lin,Yuan ^[1] ; Zhijie,Xu ^[1] ; Boyuan,Meng ^[1] ; Lan,Ye ^[2]

作者单位： Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), 3501 Daxue Road, Jinan, 250353, China.;Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), 3501 Daxue Road, Jinan, 250353, China.;Shandong Provincial Key Laboratory of Industrial Network and Information System Security, Shandong Fundamental Research Center for Computer Science, 3501 Daxue Road, Jinan, 250353, China. ^[1] Cancer Center, The Second Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, China. sdeyyelan@email.sdu.edu.cn. ^[2]

关键词 Autoencoder Clustering scRNA-seq data SimAM ZINB model Zero-inflated layer

医学主题词人类(Humans);算法(Algorithms);聚类分析(Cluster Analysis);计算生物学(Computational Biology);序列分析, RNA(Sequence Analysis, RNA);单细胞分析(Single-Cell Analysis);软件(Software)

DOI 10.1186/s12864-025-11511-2

PMID 40197174

发布时间 2025-04-18

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