Suppression of NRF2 by photodynamic action to enhance bortezomib-triggered DNA damage for synergistic colorectal cancer therapy.
第一作者:
Liu-Gen,Li
第一单位:
Shiyan Key Laboratory of Natural Medicine Nanoformulation Research, Hubei Key Laboratory of Embryonic Stem Cell Research, School of Basic Medical Sciences, Hubei University of Medicine, Renmin road No. 30, Shiyan, Hubei 442000, China.
作者:
医学主题词
NF-E2相关因子2(NF-E2-Related Factor 2);人类(Humans);光化学疗法(Photochemotherapy);结直肠肿瘤(Colorectal Neoplasms);动物(Animals);DNA损伤(DNA Damage);细胞系, 肿瘤(Cell Line, Tumor);小鼠(Mice);活性氧(Reactive Oxygen Species);细胞凋亡(Apoptosis);抗肿瘤药(Antineoplastic Agents);光敏感药(Photosensitizing Agents);卟啉类(Porphyrins);小鼠, 裸(Mice, Nude);细胞存活(Cell Survival);小鼠, 近交BALB C(Mice, Inbred BALB C);泛素化(Ubiquitination);脱植基叶绿素类(Chlorophyllides)
DOI
10.1016/j.jphotobiol.2025.113162
PMID
40199069
发布时间
2025-05-10
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