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Complementary approaches define the metabolic features that accompany Richter syndrome transformation.

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第一作者： Giulia,Omezzolli

第一单位： Department of Medical Sciences, University of Torino, Via Nizza 52, 10126, Turin, Italy.

作者： Giulia,Omezzolli ^[1] ; Andrea,Iannello ^[1] ; Francesco E,Vallone ^[1] ; Lorenzo,Brandimarte ^[1] ; Matilde,Micillo ^[1] ; Nadia,Bertola ^[2] ; Chiara,Lavarello ^[3] ; Nicole,Grinovero ^[3] ; Giulio,Ferrero ^[4] ; Kevin,Mellert ^[5] ; Peter,Möller ^[5] ; Silvia,Bruno ^[6] ; Richard R,Furman ^[7] ; John N,Allan ^[7] ; Andrea,Petretto ^[3] ; Silvia,Deaglio ^[1] ; Silvia,Ravera ^[8] ; Tiziana,Vaisitti ^[9]

作者单位： Department of Medical Sciences, University of Torino, Via Nizza 52, 10126, Turin, Italy. ^[1] U.O. Molecular Pathology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. ^[2] Core Facilities-Clinical Proteomics and Metabolomics, IRCCS Giannina Gaslini, Genoa, Italy. ^[3] Department of Clinical and Biological Sciences, University of Turin, Turin, Italy. ^[4] Institute of Pathology, University Hospital Ulm, Ulm, Germany. ^[5] Department of Experimental Medicine, University of Genoa, Genoa, Italy. ^[6] Weill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, USA. ^[7] Department of Experimental Medicine, University of Genoa, Genoa, Italy.;IRCCS Ospedale Policlinico San Martino, Genova, Italy. ^[8] Department of Medical Sciences, University of Torino, Via Nizza 52, 10126, Turin, Italy. tiziana.vaisitti@unito.it. ^[9]

关键词 Building blocks Chronic lymphocytic leukemia Metabolic dependencies Metabolic rewiring Metabolic targeting Richter transformation