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Autologous T cell therapy for PRAME<sup>+</sup> advanced solid tumors in HLA-A*02<sup>+</sup> patients: a phase 1 trial.

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第一作者: Martin,Wermke
第一单位: Department of Medicine I, University Hospital Carl Gustav Carus TU Dresden, Dresden, Germany.;National Center for Tumor Diseases, Dresden, Germany.
作者单位: Department of Medicine I, University Hospital Carl Gustav Carus TU Dresden, Dresden, Germany.;National Center for Tumor Diseases, Dresden, Germany. [1] Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [2] Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany. [3] Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [4] Department of Hematology, Oncology, Immunooncology, Stem Cell Transplantation, and Rheumatology, University Hospital Bonn, Bonn, Germany. [5] Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [6] Columbia University Medical Center, New York, NY, USA. [7] Department of Oncology and Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [8] Department of Oncology, Hematology, and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [9] Department of Medicine I, University Hospital Carl Gustav Carus TU Dresden, Dresden, Germany. [10] Immatics Biotechnologies GmbH, Tübingen, Germany. [11] Immatics US, Inc., Houston, TX, USA. [12] Institute of Immunology, Eberhard Karls University Tübingen, Tübingen, Germany. [13] Cancer Immunotherapeutics Center, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. [14] Immatics Biotechnologies GmbH, Tübingen, Germany. cedrik.britten@immatics.com. [15]
DOI 10.1038/s41591-025-03650-6
PMID 40205198
发布时间 2025-08-30
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