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Hepatic Encephalopathy and MELD-Na Predict Treatment Benefit in Autoimmune Hepatitis-related Decompensated Cirrhosis.

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第一作者: Pinelopi,Arvaniti
第一单位: Liver Unit, Hospital Clínic Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Universitat de Barcelona, Barcelona, Spain; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).
作者: Pinelopi,Arvaniti [1] ; Sergio,Rodríguez-Tajes [2] ; Marlene,Padilla [3] ; Ignasi,Olivas [2] ; Ezequiel,Mauro [4] ; Cautar,El Maimouni [4] ; Ellina,Lytvyak [5] ; Xavier,Verhelst [6] ; Bastian,Engel [7] ; Richard,Taubert [7] ; Sara,Lorente-Pérez [8] ; Isabel,Conde [9] ; Mar,Riveiro-Barciela [10] ; Juan-Carlos,Ruiz-Cobo [10] ; Carmen,Álvarez-Navascués [11] ; Magdalena,Salcedo [12] ; Judith,Gómez [13] ; Maciej K,Janik [14] ; Beatriz,Mateos [15] ; Cumali,Efe [16] ; Alessandro,Granito [17] ; Elton,Dajti [18] ; Francesco,Azzaroli [18] ; Diana,Horta [19] ; Carmen,Vila [20] ; Inmaculada,Castello [21] ; Indhira,Pérez-Medrano [22] ; Ana,Arencibia [23] ; Alessio,Gerussi [24] ; Tony,Bruns [25] ; Francesca,Colaprieto [26] ; Ana,Lleo [26] ; Natalie,Van den Ende [27] ; Jef,Verbeek [27] ; Álvaro,Díaz-González [28] ; Rosa Ma,Morillas [29] ; Maria,Torner-Simó [29] ; Vanesa,Bernal [30] ; Eva-Maria,Fernández [30] ; Tom J G,Gevers [31] ; Benedetta,Terziroli Beretta-Piccoli [32] ; Elena,Gómez [33] ; Paqui,Cuenca [34] ; Ynte S,de Boer [35] ; Nanda,Kerkar [36] ; David N,Assis [37] ; Rodrigo,Liberal [38] ; Joost P H,Drenth [39] ; Michele M,Tana [40] ; Marcial,Sebode [41] ; Ida,Schregel [41] ; Christoph,Schramm [42] ; Ansgar W,Lohse [41] ; Aldo J,Montano-Loza [5] ; Kalliopi,Zachou [43] ; Alejandra,Villamil [3] ; George N,Dalekos [43] ; María-Carlota,Londoño [44] ; International Autoimmune Hepatitis Group (IAIHG) ; European Reference Network on Hepatological Diseases (ENR RARE-LIVER) ; Spanish Registry for Autoimmune and Cholestatic Diseases (ColHai) Registry
作者单位: Liver Unit, Hospital Clínic Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Universitat de Barcelona, Barcelona, Spain; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece; European Reference Network on Hepatological Diseases (ERN RARE-LIVER). [1] Liver Unit, Hospital Clínic Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Universitat de Barcelona, Barcelona, Spain; European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain. [2] Unidad de Autoinmunidad Hepática Sección de Hepatología y Trasplante Hepático, Hospital Italiano de Buenos Aires, Argentina. [3] Liver Unit, Hospital Clínic Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Universitat de Barcelona, Barcelona, Spain. [4] Division of Gastroenterology and Liver Unit, University of Alberta, Edmonton, Alberta, Canada. [5] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Gastroenterology and Hepatology, Liver Research Center, Ghent University Hospital, Ghent, Belgium. [6] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Gastroenterology, Hepatology, Infectious Diseases, and Endocrinology, Hannover Medical School, Hannover, Germany. [7] Servicio de Hepatología, Hospital Clínico Lozano Blesa, Universidad de Zaragoza, Zaragoza, Spain. [8] Unit of Hepatology and Liver Transplantation, University Hospital La Fe. Institute of Sanitary Investigation, La Fe, Valencia, Spain. [9] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain; Liver Unit, Department of Internal Medicine, University Hospital Vall de Hebron, Barcelona, Spain. [10] Servicio de Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, Spain. [11] Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain; Sección de Hepatología, Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, Spain. [12] Servicio de Aparato Digestivo, Hospital Universitario de Burgos, Burgos, Spain. [13] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Hepatology, Transplantology, and Internal Medicine, Medical University of Warsaw, Warsaw, Poland. [14] Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain; Servicio de Aparato Digestivo, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain. [15] Department of Gastroenterology, Harran University, Şanlıurfa, Turkey. [16] IRCCS Azienda Ospedaliero-Universitaria di Bologna, Center for the Study and Treatment of Autoimmune Diseases of the Liver and Biliary System, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. [17] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Gastroenterology Units, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. [18] Servicio de Aparato Digestivo, Hospital Universitario Mutua de Terrassa, Terrassa, Spain. [19] Servicio Digestivo (Endumsalut), Hospital Universitario Quirón Dexeus, Barcelona, Spain. [20] Servicio de Aparato Digestivo, Hospital General Universitario de Valencia, Valencia, Spain. [21] Complexo Hospitalario Universitario de Pontevedra, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Pontevedra, Spain. [22] Servicio de Aparato Digestivo, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain. [23] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Division of Gastroenterology and Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza (MB), Italy. [24] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Medicine III, University Hospital RWTH Aachen, European Reference Network on Liver Disease (ERN Rare-Liver), Aachen, Germany. [25] Department of Biomedical Sciences, Humanitas University, Milan, Italy; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy. [26] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Gastroenterology and Hepatology, University Hospitals KU Leuven, Leuven, Belgium. [27] Gastroenterology and Hepatology Department, Clinical and Translational Research in Digestive Diseases Group, Valdecilla Research Institute (IDIVAL), Marqués de Valdecilla University Hospital, Santander, Spain. [28] Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain; Department of Hepatology, Hospital Germans Trias i Pujol, Institute of Investigation Germans Trias i Pujol (IGTP), Badalona, Spain. [29] Servicio de Aparato Digestivo, Hospital Universitario Miguel Servet, Zaragoza, Spain. [30] Department of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, The Netherlands. [31] Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Epatocentro Ticino, Lugano, Switzerland. [32] Servicio de Aparato Digestivo, Hospital Universitario 12 de Octubre, Madrid, Spain. [33] Servicio de Aparato Digestivo, Hospital Clínico San Carlos, Madrid, Spain. [34] Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands. [35] Division of Gastroenterology, Hepatology, and Nutrition, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, Section of Pediatric Hepatology and Liver Transplantation, Massachusetts General Hospital for Children, Harvard University, Boston, Massachusetts. [36] Section of Digestive Diseases, Yale School of Medicine, New Haven, Connecticut. [37] Gastroenterology Department, Centro Hospitalar Universitário de São João, Facultyof Medicine of the University of Porto, Porto, Portugal. [38] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands. [39] Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, California. [40] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Medicine, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany. [41] European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Department of Medicine, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany; Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [42] Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece; European Reference Network on Hepatological Diseases (ERN RARE-LIVER). [43] Liver Unit, Hospital Clínic Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Universitat de Barcelona, Barcelona, Spain; European Reference Network on Hepatological Diseases (ERN RARE-LIVER); Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain. Electronic address: mlondono@clinic.cat. [44]
DOI 10.1016/j.cgh.2025.02.010
PMID 40210079
发布时间 2026-03-23
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Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

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