Glycogen stores mediated by the p53-GYS1 feedback circuit engenders platinum resistance in ovarian clear cell carcinoma.
第一作者:
Hao-Yu,Liang
第一单位:
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P. R. China.;Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P. R. China.
作者:
医学主题词
人类(Humans);女(雌)性(Female);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);卵巢肿瘤(Ovarian Neoplasms);糖原(Glycogen);抗药性, 肿瘤(Drug Resistance, Neoplasm);腺癌, 透明细胞(Adenocarcinoma, Clear Cell);细胞系, 肿瘤(Cell Line, Tumor);铂(Platinum);糖原合成酶(Glycogen Synthase);反馈, 生理(Feedback, Physiological);动物(Animals)
DOI
10.1038/s41418-025-01500-z
PMID
40210982
发布时间
2025-09-16
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Cell death and differentiation
1707-1721页
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