Therapeutic Targets in Glioblastoma: Molecular Pathways, Emerging Strategies, and Future Directions.

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第一作者： Justin,Tang

第一单位： Department of Biomedical Science, University of Guelph, Guelph, ON N1G 2W1, Canada.;Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.

作者： Justin,Tang ^[1] ; Nishika,Karbhari ^[2] ; Jian L,Campian ^[2]

作者单位： Department of Biomedical Science, University of Guelph, Guelph, ON N1G 2W1, Canada.;Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA. ^[1] Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA. ^[2]

关键词 CAR T cell therapy MGMT promoter methylation biomarkers blood–brain barrier combination therapies drug delivery systems epigenetic modulation gene therapy glioblastoma immunotherapy molecular pathways nanotechnology oncolytic viruses targeted therapy tumor microenvironment

主题词人类(Humans);胶质母细胞瘤(Glioblastoma);脑肿瘤(Brain Neoplasms);血脑屏障(Blood-Brain Barrier);分子靶向治疗(Molecular Targeted Therapy);动物(Animals);药物释放系统(Drug Delivery Systems);免疫疗法(Immunotherapy);信号传导(Signal Transduction)

DOI 10.3390/cells14070494

PMID 40214448

发布时间 2025-04-13

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2025年14卷7期

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