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Effects of life-long hyperlipidaemia on age-dependent development of endothelial dysfunction in humanised dyslipidaemic mice.

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第一作者： Anna,Bar

第一单位： Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30-348, Krakow, Poland.

作者： Anna,Bar ^[1] ; Piotr,Berkowicz ^[1] ; Anna,Kurpinska ^[1] ; Tasnim,Mohaissen ^[2] ; Agnieszka,Karaś ^[1] ; Patrycja,Kaczara ^[1] ; Joanna,Suraj-Prażmowska ^[1] ; Magdalena,Sternak ^[1] ; Brygida,Marczyk ^[1] ; Agata,Malinowska ^[3] ; Agnieszka,Kij ^[1] ; Agnieszka,Jasztal ^[1] ; Izabela,Czyzynska-Cichon ^[1] ; Elsbet J,Pieterman ^[4] ; Hans M G,Princen ^[4] ; Jacek R,Wiśniewski ^[5] ; Stefan,Chlopicki ^[6]

作者单位： Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30-348, Krakow, Poland. ^[1] Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30-348, Krakow, Poland.;University of Copenhagen, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, Blegdamsvej 3B, 2200 København, Copenhagen, Denmark. ^[2] Polish Academy of Sciences, Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Pawińskiego St 5a, 02-106, Warsaw, Poland. ^[3] The Netherlands Organisation of Applied Scientific Research (TNO), Metabolic Health Research, Gaubius Laboratory, 2333 CK, Leiden, The Netherlands. ^[4] Max Planck Institute of Biochemistry, Department of Proteomics and Signal Transduction, Am Klopferspitz 18, 82152 Planegg, Martinsried, Germany. ^[5] Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30-348, Krakow, Poland. stefan.chlopicki@jcet.eu.;Jagiellonian University Medical College, Faculty of Medicine, Grzegorzecka 16, 31-531, Krakow, Poland. stefan.chlopicki@jcet.eu. ^[6]

关键词 APOE?3-Leiden.huCETP mice Ageing Endothelial dysfunction Hyperlipidaemia Magnetic resonance imaging