TNF-α/NF-κB mediated upregulation of Dectin-1 in hyperglycemic obesity: implications for metabolic inflammation and diabetes.
第一作者:
Ashraf,Al Madhoun
第一单位:
Department of Animal and Imaging Core Facilities, Dasman Diabetes Institute, Al-Soor Street, P.O. Box 1180, Dasman, 15462, Kuwait. ashraf.madhoun@dasmaninstitute.org.;Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman, Kuwait. ashraf.madhoun@dasmaninstitute.org.
作者:
医学主题词
人类(Humans);NF-κB(NF-kappa B);动物(Animals);肥胖症(Obesity);增量调节(Up-Regulation);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);外源凝集素类, C型(Lectins, C-Type);高血糖症(Hyperglycemia);炎症(Inflammation);男(雄)性(Male);小鼠(Mice);女(雌)性(Female);糖尿病(Diabetes Mellitus);中年人(Middle Aged);成年人(Adult);脂肪组织(Adipose Tissue);启动区, 遗传(Promoter Regions, Genetic);脂细胞(Adipocytes);小鼠, 近交C57BL(Mice, Inbred C57BL)
DOI
10.1186/s12967-025-06303-x
PMID
40270030
发布时间
2025-04-24
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