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Arginine Therapy for Pain in Sickle Cell Disease: A Phase-2 Randomized, Placebo-Controlled Trial.

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第一作者： Claudia R,Morris

第一单位： Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.;Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.;Children's Healthcare of Atlanta, Atlanta, Georgia, USA.

作者： Claudia R,Morris ^[1] ; Dunia,Hatabah ^[2] ; Rawan,Korman ^[2] ; Scott,Gillespie ^[2] ; Nitya,Bakshi ^[3] ; Lou Ann,Brown ^[2] ; Frank,Harris ^[2] ; Deborah,Leake ^[4] ; Chris A,Rees ^[1] ; Kirshma,Khemani ^[5] ; Elliott P,Vichinsky ^[6] ; Alexus,Locke ^[4] ; Bridget,Wynn ^[2] ; Mark A,Griffiths ^[1] ; Hagar,Wilkinson ^[4] ; Polly,Kumari ^[2] ; Lisa,Sudmeier ^[7] ; Sruti,Shiva ^[8] ; Carlton D,Dampier ^[5]

作者单位： Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.;Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.;Children's Healthcare of Atlanta, Atlanta, Georgia, USA. ^[1] Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA. ^[2] Yale School of Medicine, New Haven, Connecticut, USA. ^[3] Children's Healthcare of Atlanta, Atlanta, Georgia, USA. ^[4] Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.;Children's Healthcare of Atlanta, Atlanta, Georgia, USA. ^[5] Department of Hematology/Oncology, UCSF Benioff Children's Hospital Oakland, Oakland, California, USA. ^[6] Department of Radiation Oncology, Emory University School of Medicine, Atlanta, Georgia, USA. ^[7] Department of Pharmacology and Chemical Biology, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. ^[8]

关键词 arginine mitochondrial function sickle cell disease vaso‐occlusive pain episodes