首页> Clinical and translational medicine> SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability: SETD2 loss in Chronic Myeloid Leukemia.

SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability: SETD2 loss in Chronic Myeloid Leukemia.

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第一作者： Manuela,Mancini

第一单位： IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", Bologna, Italy.

作者： Manuela,Mancini ^[1] ; Sara,De Santis ^[2] ; Cecilia,Monaldi ^[2] ; Fausto,Castagnetti ^[2] ; Miriam,Iezza ^[2] ; Alessandra,Iurlo ^[3] ; Daniele,Cattaneo ^[4] ; Sara,Galimberti ^[5] ; Marco,Cerrano ^[6] ; Isabella,Capodanno ^[7] ; Massimiliano,Bonifacio ^[8] ; Maura,Rossi ^[1] ; Claudio,Agostinelli ^[9] ; Manja,Meggendorfer ^[10] ; Torsten,Haferlach ^[10] ; Michele,Cavo ^[1] ; Gabriele,Gugliotta ^[1] ; Simona,Soverini ^[2]

作者单位： IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", Bologna, Italy. ^[1] Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. ^[2] Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy. ^[3] Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.;Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy. ^[4] Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy. ^[5] Azienda Ospedaliera Citta' Della Salute E Della Scienza Di Torino, Torino, Italy. ^[6] SOC Ematologia Azienda USL-IRCSS di Reggio Emilia, Reggio Emilia, Italy. ^[7] Section of Hematology, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy. ^[8] IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", Bologna, Italy.;Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ^[9] MLL Munich Leukemia Laboratory, Munich, Germany. ^[10]

关键词 Aurora kinase A H3K36me3 MDM2 SETD2 genomic instability

医学主题词人类(Humans);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);白血病, 髓系, 慢性, BCR-ABL阳性(Leukemia, Myelogenous, Chronic, BCR-ABL Positive);基因组不稳定性(Genomic Instability);组蛋白类(Histones)

DOI 10.1002/ctm2.70163

PMID 40275711

发布时间 2025-04-27

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