换一批DNA-methylation eraser TET2 activates WTIP expression to suppress an AKT-dependent chemoresistance of gastric cancer.
第一作者：
Yan,Guo
第一单位：
Department of Gastroenterology, Chongqing Key Laboratory of Digestive Malignancies, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing 400042, China.
作者：
医学主题词
人类(Humans);胃肿瘤(Stomach Neoplasms);抗药性, 肿瘤(Drug Resistance, Neoplasm);DNA结合蛋白质类(DNA-Binding Proteins);双加氧酶类(Dioxygenases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质类(Proto-Oncogene Proteins);DNA甲基化(DNA Methylation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);细胞系, 肿瘤(Cell Line, Tumor);动物(Animals);小鼠(Mice);载体蛋白质类(Carrier Proteins)
DOI
10.1016/j.neo.2025.101166
PMID
40279682
发布时间
2025-09-18
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Neoplasia (New York, N.Y.)
101166页
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