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Donor-reactive T cells and innate immune cells promote pig-to-human decedent xenograft rejection.

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第一作者： Farshid,Fathi

第一单位： Department of Medicine, Columbia Center for Translational Immunology, Columbia University Medical Center, Columbia University; New York, NY, USA.

作者： Farshid,Fathi ^[1] ; Nathan,Suek ^[1] ; Benjamin,Vermette ^[1] ; Kevin,Breen ^[1] ; Yasmeen S,Saad ^[1] ; Constanza,Bay ^[1] ; Christopher A,Parks ^[1] ; Jeffrey,Stern ^[2] ; Karen,Khalil ^[2] ; Jacqueline,Kim ^[2] ; Ian S,Jaffe ^[2] ; Imad,Aljabban ^[2] ; Ekaterina,Novikova ^[3] ; Elizabeth,Severa ^[3] ; Ramin Sedaghat,Herati ^[3] ; Lars,Burdorf ^[4] ; Adam D,Griesemer ^[2] ; Robert A,Montgomery ^[2] ; Megan,Sykes ^[1]

作者单位： Department of Medicine, Columbia Center for Translational Immunology, Columbia University Medical Center, Columbia University; New York, NY, USA. ^[1] Department of Surgery, Transplant Institute, New York University Langone Health; New York, NY, USA. ^[2] Department of Medicine, NYU Grossman School of Medicine; New York, NY, USA. ^[3] United Therapeutics Corporation; Research Triangle Park, NC, USA. ^[4]

DOI 10.21203/rs.3.rs-6474835/v1

PMID 40313748

发布时间 2025-05-05

基金项目

P30 CA016087/CA/NCI NIH HHS/United States S10 OD020056/OD/NIH HHS/United States S10 OD030282/OD/NIH HHS/United States UL1 TR001445/TR/NCATS NIH HHS/United States

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Donor-reactive T cells and innate immune cells promote pig-to-human decedent xenograft rejection.

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Donor-reactive T cells and innate immune cells promote pig-to-human decedent xenograft rejection.

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