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Plasma protein corona of liposomes loaded with a phospholipid-allocolchicinoid conjugate enhances their anti-inflammatory potential.

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第一作者： Ekaterina,Ryabukhina

第一单位： Laboratory of Lipid Chemistry, Department of Chemical Biology of Glycans and Lipids, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

作者： Ekaterina,Ryabukhina ^[1] ; Maria,Kobanenko ^[1] ; Daria,Tretiakova ^[1] ; Ekaterina,Shchegravina ^[2] ; Sergey,Khaidukov ^[3] ; Anna,Alekseeva ^[1] ; Ivan,Boldyrev ^[4] ; Viktor,Zgoda ^[5] ; Olga,Tikhonova ^[5] ; Alexey Yu,Fedorov ^[2] ; Natalia,Onishchenko ^[6] ; Elena,Vodovozova ^[7]

作者单位： Laboratory of Lipid Chemistry, Department of Chemical Biology of Glycans and Lipids, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia. ^[1] Department of Chemistry, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod 603950, Russia. ^[2] Laboratory of Carbohydrates, Department of Chemical Biology of Glycans and Lipids, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia. ^[3] Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia. ^[4] Institute of Biomedical Chemistry, Moscow 119121, Russia. ^[5] Laboratory of Lipid Chemistry, Department of Chemical Biology of Glycans and Lipids, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia; Center for Algorithmic and Robotized Synthesis, Institute for Basic Science, Ulsan 44919, Republic of Korea. ^[6] Laboratory of Lipid Chemistry, Department of Chemical Biology of Glycans and Lipids, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia. Electronic address: elvod@lipids.ibch.ru. ^[7]

关键词 Allocolchicinoid-lipid conjugate Anti-inflammatory effect Liposome Protein corona