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Depletion of oxysterol-binding proteins by OSW-1 triggers RIP1/RIP3-independent necroptosis and sensitization to cancer immunotherapy.

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第一作者： Xinyan,Lu

第一单位： Department of Medicine, Keck School of Medicine of University of Southern California (USC), Los Angeles, CA, USA.;Norris Comprehensive Cancer Center, Keck School of Medicine of USC, Los Angeles, CA, USA.;Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.;UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

作者： Xinyan,Lu ^[1] ; Dongshi,Chen ^[1] ; Min,Wang ^[2] ; Xiangping,Song ^[2] ; Kaylee,Ermine ^[2] ; Suisui,Hao ^[1] ; Anupma,Jha ^[2] ; Yixian,Huang ^[3] ; Ying,Kang ^[4] ; Haibo,Qiu ^[4] ; Heinz-Josef,Lenz ^[5] ; Song,Li ^[3] ; Zhendong,Jin ^[4] ; Jian,Yu ^[1] ; Lin,Zhang ^[6]

作者单位： Department of Medicine, Keck School of Medicine of University of Southern California (USC), Los Angeles, CA, USA.;Norris Comprehensive Cancer Center, Keck School of Medicine of USC, Los Angeles, CA, USA.;Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.;UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[1] Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.;UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[2] UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.;Department of Pharmaceutical Sciences, Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA. ^[3] Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA. ^[4] Department of Medicine, Keck School of Medicine of University of Southern California (USC), Los Angeles, CA, USA.;Norris Comprehensive Cancer Center, Keck School of Medicine of USC, Los Angeles, CA, USA. ^[5] Department of Medicine, Keck School of Medicine of University of Southern California (USC), Los Angeles, CA, USA. lzhang24@usc.edu.;Norris Comprehensive Cancer Center, Keck School of Medicine of USC, Los Angeles, CA, USA. lzhang24@usc.edu.;Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. lzhang24@usc.edu.;UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. lzhang24@usc.edu. ^[6]