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SARS-CoV-2 induced immune perturbations in infants vary with disease severity and differ from adults' responses.

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第一作者: Djamel,Nehar-Belaid
第一单位: The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
作者单位: The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA. [1] Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.;Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA.;Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. [2] Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA.;Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. [3] Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA. [4] Department of Pediatrics, Division of Neonatology and Center for Perinatal Research, Ohio Perinatal Research Network, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA. [5] Center for Systems and Engineering Immunology, Departments of Immunobiology and Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.;Department of Biomedical Engineering, Yale University, New Haven, CT, USA.;Chan Zuckerberg Biohub NY, New Haven, CT, USA. [6] Department of Microbiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. [7] Department of Microbiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.;Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.;Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.;The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.;Department of Pathology, Molecular and Cell-Based Medicine, One Gustave L. Levy Place, New York, NY, 10029, USA.;Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. [8] The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA. jacques.banchereau@gmail.com.;Immunoledge LLC, Montclair, NJ, USA. jacques.banchereau@gmail.com. [9] Drukier Institute for Children's Health and Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA. vip2021@med.cornell.edu. [10] Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA. octavio.ramilo@stjude.org.;Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA. octavio.ramilo@stjude.org.;Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. octavio.ramilo@stjude.org. [11]
DOI 10.1038/s41467-025-59411-z
PMID 40379618
发布时间 2026-04-06
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