换一批Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
第一作者：
Rowan,Saloner
第一单位：
Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. rowan.saloner@ucsf.edu.
作者：
Rowan,Saloner [1]
;
Adam M,Staffaroni [2]
;
Eric B,Dammer [3]
;
Erik C B,Johnson [3]
;
Emily W,Paolillo [2]
;
Amy,Wise [2]
;
Hilary W,Heuer [2]
;
Leah K,Forsberg [4]
;
Argentina,Lario-Lago [2]
;
Julia D,Webb [2]
;
Jacob W,Vogel [5]
;
Alexander F,Santillo [6]
;
Oskar,Hansson [7]
;
Joel H,Kramer [2]
;
Bruce L,Miller [2]
;
Jingyao,Li [8]
;
Joseph,Loureiro [8]
;
Rajeev,Sivasankaran [8]
;
Kathleen A,Worringer [8]
;
Nicholas T,Seyfried [9]
;
Jennifer S,Yokoyama [10]
;
Salvatore,Spina [2]
;
Lea T,Grinberg [11]
;
William W,Seeley [11]
;
Lawren,VandeVrede [2]
;
Peter A,Ljubenkov [2]
;
Ece,Bayram [12]
;
Andrea,Bozoki [13]
;
Danielle,Brushaber [14]
;
Ciaran M,Considine [15]
;
Gregory S,Day [16]
;
Bradford C,Dickerson [17]
;
Kimiko,Domoto-Reilly [18]
;
Kelley,Faber [19]
;
Douglas R,Galasko [12]
;
Tania,Gendron [16]
;
Daniel H,Geschwind [20]
;
Nupur,Ghoshal [21]
;
Neill,Graff-Radford [22]
;
Chadwick M,Hales [23]
;
Lawrence S,Honig [24]
;
Ging-Yuek R,Hsiung [25]
;
Edward D,Huey [24]
;
John,Kornak [26]
;
Walter,Kremers [14]
;
Maria I,Lapid [27]
;
Suzee E,Lee [2]
;
Irene,Litvan [12]
;
Corey T,McMillan [28]
;
Mario F,Mendez [20]
;
Toji,Miyagawa [4]
;
Alexander,Pantelyat [29]
;
Belen,Pascual [30]
;
Joseph,Masdeu [30]
;
Henry L,Paulson [31]
;
Leonard,Petrucelli [16]
;
Peter,Pressman [32]
;
Rosa,Rademakers [33]
;
Eliana Marisa,Ramos [20]
;
Katya,Rascovsky [28]
;
Erik D,Roberson [34]
;
Rodolfo,Savica [4]
;
Allison,Snyder [35]
;
Anna Campbell,Sullivan [36]
;
M Carmela,Tartaglia [37]
;
Marijne,Vandebergh [33]
;
Brad F,Boeve [4]
;
Howie J,Rosen [2]
;
Julio C,Rojas [2]
;
Adam L,Boxer [2]
;
Kaitlin B,Casaletto [2]
;
ALLFTD Consortium
作者单位：
Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. rowan.saloner@ucsf.edu.
[1]
Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
[2]
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.;Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
[3]
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
[4]
Department of Clinical Sciences, SciLifeLab, Lund University, Lund, Sweden.
[5]
Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.
[6]
Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.;Memory Clinic, Skåne University Hospital, Malmö, Sweden.
[7]
Novartis Institutes for Biomedical Research, Inc, Cambridge, MA, USA.
[8]
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.;Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.;Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
[9]
Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.;Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
[10]
Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.;Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.
[11]
Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
[12]
Department of Neurology, University of North Carolina, Chapel Hill, NC, USA.
[13]
Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
[14]
Department of Neurology, Vanderbilt University, Nashville, TN, USA.
[15]
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
[16]
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
[17]
Department of Neurology, University of Washington, Seattle, WA, USA.
[18]
Indiana University School of Medicine, National Centralized Repository for Alzheimer's, Indianapolis, IN, USA.
[19]
Department of Neurology, University of California, Los Angeles, Los Angeles, USA.
[20]
Departments of Neurology and Psychiatry, Washington University School of Medicine, Washington University, St. Louis, MO, USA.
[21]
Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.
[22]
Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
[23]
Department of Neurology, Columbia University, New York, NY, USA.
[24]
Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada.
[25]
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
[26]
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
[27]
Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
[28]
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
[29]
Department of Neurology, Houston Methodist, Houston, TX, USA.
[30]
Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
[31]
Department of Neurology, University of Colorado, Aurora, CO, USA.
[32]
VIB Center for Molecular Neurology, University of Antwerp, Antwerp, Belgium.
[33]
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
[34]
National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
[35]
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.
[36]
Tanz Centre for Research in Neurodegenerative Diseases, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
[37]
医学主题词
人类(Humans);额颞叶变性(Frontotemporal Lobar Degeneration);男(雄)性(Male);蛋白质组学(Proteomics);女(雌)性(Female);蛋白质组(Proteome);中年人(Middle Aged);tau蛋白质类(tau Proteins);老年人(Aged);成年人(Adult);突变(Mutation)
DOI
10.1038/s43587-025-00878-2
PMID
40380000
发布时间
2026-04-04
- 浏览0
Nature aging
Nature aging
2025年5卷6期
1143-1158页
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