Acute administration of lovastatin had no pronounced effect on motor abilities, motor coordination, gait nor simple cognition in a mouse model of Angelman syndrome.
第一作者:
Timothy A,Fenton
第一单位:
MIND Institute, University of California Davis School of Medicine, Room 1001 A, Research II Building 96, 4625 2nd Avenue, Sacramento, CA, 95817, USA.;Department of Psychiatry and Behavioral Sciences, University of California Davis School of Medicine, Sacramento, CA, USA.
作者:
医学主题词
动物(Animals);洛伐他汀(Lovastatin);Angelman综合征(Angelman Syndrome);疾病模型, 动物(Disease Models, Animal);小鼠(Mice);步态(Gait);男(雄)性(Male);认知(Cognition);女(雌)性(Female);行为, 动物(Behavior, Animal);小鼠, 近交C57BL(Mice, Inbred C57BL);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);运动活动(Motor Activity)
DOI
10.1186/s11689-025-09616-6
PMID
40382580
发布时间
2025-05-20
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